High frequency stimulation can block axonal conduction
نویسندگان
چکیده
منابع مشابه
Spatiotemporally Controlled Cardiac Conduction Block Using High-Frequency Electrical Stimulation
BACKGROUND Methods for the electrical inhibition of cardiac excitation have long been sought to control excitability and conduction, but to date remain largely impractical. High-amplitude alternating current (AC) stimulation has been known to extend cardiac action potentials (APs), and has been recently exploited to terminate reentrant arrhythmias by producing reversible conduction blocks. Yet,...
متن کاملAsymmetric Rectangular Waveform in Stimulation with High Frequency Alternating Current Reduces the Threshold for Neural Conduction Block
Introduction Abnormal neural impulses in the nervous system may lead to various diseases and disabilities. High frequency alternating currents (HFAC) has been used to block the propagation of such impulses and improve the symptoms or disabilities. The technique is safe, reversible, and relatively selective, and its reliability, the optimum stimulation parameters, and elimination of the onset re...
متن کاملConduction block in acute motor axonal neuropathy.
Guillain-Barré syndrome is divided into two major subtypes, acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. The characteristic electrophysiological features of acute motor axonal neuropathy are reduced amplitude or absence of distal compound muscle action potentials indicating axonal degeneration. In contrast, autopsy study results show early nodal changes in ...
متن کاملConduction block in myelinated axons induced by high-frequency (kHz) non-symmetric biphasic stimulation
This study used the Frankenhaeuser-Huxley axonal model to analyze the effects of non-symmetric waveforms on conduction block of myelinated axons induced by high-frequency (10-300 kHz) biphasic electrical stimulation. The results predict a monotonic relationship between block threshold and stimulation frequency for symmetric waveform and a non-monotonic relationship for non-symmetric waveforms. ...
متن کاملasymmetric rectangular waveform in stimulation with high frequency alternating current reduces the threshold for neural conduction block
introduction abnormal neural impulses in the nervous system may lead to various diseases and disabilities. high frequency alternating currents (hfac) has been used to block the propagation of such impulses and improve the symptoms or disabilities. the technique is safe, reversible, and relatively selective, and its reliability, the optimum stimulation parameters, and elimination of the onset re...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2009
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2009.07.023